With his best pal gone, Deadpool continues his trek through time and space, spreading friendship and mercenary whoop-&*$ throughout the cosmos. Featuring titanic team-ups with Wolverine, Captain America, Dr. Strange, Brother Voodoo, Ka-Zar and the Fantastic…Eight?! And in the unforgettable series finale, the dreaded Venom Symbiote has multiplied, and made some new friends of the prehistoric variety, giving the Merc with a Mouth his final opportunity to prove himself the ultimate hero – or the ultimate villain! Guest-starring Spider-Man! The Fantastic Four! The Mighty Avengers! And of course, those lovable goons from Agency X! Collecting CABLE & DEADPOOL #43-50.